Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphatidylcholine:ceramide cholinephosphotransferase 2
(Homo sapiens (Human)) | BDBM50529847
(CHEMBL4516049)Show InChI InChI=1S/C22H21ClN2O4/c1-27-11-12-28-20-9-8-17(23)13-16(20)15-29-21-7-3-2-6-19(21)22(26)25-18-5-4-10-24-14-18/h2-10,13-14H,11-12,15H2,1H3,(H,25,26) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University
Curated by ChEMBL
| Assay Description Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol... |
Eur J Med Chem 163: 864-882 (2019)
Article DOI: 10.1016/j.ejmech.2018.12.028 BindingDB Entry DOI: 10.7270/Q2NZ8C4J |
More data for this Ligand-Target Pair | |
Phosphatidylcholine:ceramide cholinephosphotransferase 2
(Homo sapiens (Human)) | BDBM50529847
(CHEMBL4516049)Show InChI InChI=1S/C22H21ClN2O4/c1-27-11-12-28-20-9-8-17(23)13-16(20)15-29-21-7-3-2-6-19(21)22(26)25-18-5-4-10-24-14-18/h2-10,13-14H,11-12,15H2,1H3,(H,25,26) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fudan University
Curated by ChEMBL
| Assay Description Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol... |
Eur J Med Chem 163: 864-882 (2019)
Article DOI: 10.1016/j.ejmech.2018.12.028 BindingDB Entry DOI: 10.7270/Q2NZ8C4J |
More data for this Ligand-Target Pair | |