Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197617
(US9216968, 217 | US9732066, 217)Show SMILES COCc1nc2c(cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H21F3N4O3/c1-35-14-21-31-20-12-16(30-24(34)17-9-5-6-10-19(17)25(26,27)28)11-18(22(20)32-21)23(33)29-13-15-7-3-2-4-8-15/h2-12H,13-14H2,1H3,(H,29,33)(H,30,34)(H,31,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINY AKU CO., LTD.
US Patent
| Assay Description mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9732066 (2017)
BindingDB Entry DOI: 10.7270/Q2K35WSW |
More data for this Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197617
(US9216968, 217 | US9732066, 217)Show SMILES COCc1nc2c(cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H21F3N4O3/c1-35-14-21-31-20-12-16(30-24(34)17-9-5-6-10-19(17)25(26,27)28)11-18(22(20)32-21)23(33)29-13-15-7-3-2-4-8-15/h2-12H,13-14H2,1H3,(H,29,33)(H,30,34)(H,31,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINYAKU CO., LTD.
US Patent
| Assay Description mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9216968 (2015)
BindingDB Entry DOI: 10.7270/Q2KS6QCQ |
More data for this Ligand-Target Pair | |