Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197644
(US9216968, 244 | US9732066, 244)Show SMILES COCc1nc2c(cc(NC(=O)c3ncccc3F)cc2[nH]1)C(=O)Nc1cccc(Cl)c1C Show InChI InChI=1S/C23H19ClFN5O3/c1-12-15(24)5-3-7-17(12)29-22(31)14-9-13(10-18-20(14)30-19(28-18)11-33-2)27-23(32)21-16(25)6-4-8-26-21/h3-10H,11H2,1-2H3,(H,27,32)(H,28,30)(H,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 56.2 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINY AKU CO., LTD.
US Patent
| Assay Description
mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9732066 (2017)
BindingDB Entry DOI: 10.7270/Q2K35WSW |
More data for this
Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197644
(US9216968, 244 | US9732066, 244)Show SMILES COCc1nc2c(cc(NC(=O)c3ncccc3F)cc2[nH]1)C(=O)Nc1cccc(Cl)c1C Show InChI InChI=1S/C23H19ClFN5O3/c1-12-15(24)5-3-7-17(12)29-22(31)14-9-13(10-18-20(14)30-19(28-18)11-33-2)27-23(32)21-16(25)6-4-8-26-21/h3-10H,11H2,1-2H3,(H,27,32)(H,28,30)(H,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 56.2 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINYAKU CO., LTD.
US Patent
| Assay Description
mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9216968 (2015)
BindingDB Entry DOI: 10.7270/Q2KS6QCQ |
More data for this
Ligand-Target Pair | |