Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228192
(1-{(R)-4-[4-(2-Cyclopropyl-pyrimidin-5-yl)-2-trifl...)Show SMILES COCc1ncn(CC(=O)N2C(C)CNCC2c2sc(cc2-c2cnc(nc2)C2CC2)C(F)(F)F)n1 Show InChI InChI=1S/C23H26F3N7O2S/c1-13-6-27-9-17(33(13)20(34)10-32-12-30-19(31-32)11-35-2)21-16(5-18(36-21)23(24,25)26)15-7-28-22(29-8-15)14-3-4-14/h5,7-8,12-14,17,27H,3-4,6,9-11H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | 7.4 | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228192
(1-{(R)-4-[4-(2-Cyclopropyl-pyrimidin-5-yl)-2-trifl...)Show SMILES COCc1ncn(CC(=O)N2C(C)CNCC2c2sc(cc2-c2cnc(nc2)C2CC2)C(F)(F)F)n1 Show InChI InChI=1S/C23H26F3N7O2S/c1-13-6-27-9-17(33(13)20(34)10-32-12-30-19(31-32)11-35-2)21-16(5-18(36-21)23(24,25)26)15-7-28-22(29-8-15)14-3-4-14/h5,7-8,12-14,17,27H,3-4,6,9-11H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |