Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lanosterol synthase
(Homo sapiens (Human)) | BDBM50494909
(CHEMBL3098183)Show SMILES COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)N[C@@H](C(C)C)C(=O)NC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C32H41N7O9/c1-14(2)22(30(44)34-10-19-25(42)26(43)31(48-19)39-13-37-23-28(33)35-12-36-29(23)39)38-20(40)9-7-15(3)6-8-17-24(41)21-18(11-47-32(21)45)16(4)27(17)46-5/h6,12-14,19,22,25-26,31,41-43H,7-11H2,1-5H3,(H,34,44)(H,38,40)(H2,33,35,36)/b15-6+/t19-,22+,25-,26-,31-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description
Inhibition of IMPDH1 (unknown origin) |
Bioorg Med Chem Lett 24: 332-6 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.005
BindingDB Entry DOI: 10.7270/Q2BP05RJ |
More data for this
Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50494909
(CHEMBL3098183)Show SMILES COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)N[C@@H](C(C)C)C(=O)NC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C32H41N7O9/c1-14(2)22(30(44)34-10-19-25(42)26(43)31(48-19)39-13-37-23-28(33)35-12-36-29(23)39)38-20(40)9-7-15(3)6-8-17-24(41)21-18(11-47-32(21)45)16(4)27(17)46-5/h6,12-14,19,22,25-26,31,41-43H,7-11H2,1-5H3,(H,34,44)(H,38,40)(H2,33,35,36)/b15-6+/t19-,22+,25-,26-,31-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description
Inhibition of IMPDH2 (unknown origin) |
Bioorg Med Chem Lett 24: 332-6 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.005
BindingDB Entry DOI: 10.7270/Q2BP05RJ |
More data for this
Ligand-Target Pair | |