Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 444.4 BDBM372582

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372582 (N-[2-(3,5-Difluoro-4-methoxy-benzyl)-2H-[1,2,3]tri...) Show SMILES COc1c(F)cc(Cn2ncc(NC(=O)Cc3ccc(OCC4COC4)cc3)n2)cc1F Show InChI InChI=1S/C22H22F2N4O4/c1-30-22-18(23)6-15(7-19(22)24)10-28-25-9-20(27-28)26-21(29)8-14-2-4-17(5-3-14)32-13-16-11-31-12-16/h2-7,9,16H,8,10-13H2,1H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
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