Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 414.4 BDBM372523

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372523 (2-(4-tert-Butyl-phenyl)-N-[2-(3,5-difluoro-4-metho...) Show SMILES COc1c(F)cc(Cn2ncc(NC(=O)Cc3ccc(cc3)C(C)(C)C)n2)cc1F Show InChI InChI=1S/C22H24F2N4O2/c1-22(2,3)16-7-5-14(6-8-16)11-20(29)26-19-12-25-28(27-19)13-15-9-17(23)21(30-4)18(24)10-15/h5-10,12H,11,13H2,1-4H3,(H,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair