Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 372.4 BDBM50198615

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM50198615 (CHEMBL3922663) Show SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc3ccccc3c2)ccc1O Show InChI InChI=1S/C24H20O4/c1-28-24-15-18(9-13-23(24)27)8-12-22(26)16-21(25)11-7-17-6-10-19-4-2-3-5-20(19)14-17/h2-15,27H,16H2,1H3/b11-7+,12-8+	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Doshisha University Curated by ChEMBL					Assay Description Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...				Bioorg Med Chem Lett 26: 5024-5028 (2016) Article DOI: 10.1016/j.bmcl.2016.08.092 BindingDB Entry DOI: 10.7270/Q2833V0M
					More data for this Ligand-Target Pair