Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 431.5 BDBM365218

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM365218 (1-(3-(2-(1-methyl-1H-pyrazol-4-yl)-6-(4-methylpyri...) Show SMILES COc1cc(C)ccc1C(=O)N1CCCC(C1)c1cc(Nc2cc(C)ccn2)nc(C)n1 Show InChI InChI=1S/C25H29N5O2/c1-16-7-8-20(22(12-16)32-4)25(31)30-11-5-6-19(15-30)21-14-24(28-18(3)27-21)29-23-13-17(2)9-10-26-23/h7-10,12-14,19H,5-6,11,15H2,1-4H3,(H,26,27,28,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	20.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...				J Med Chem 50: 3515-27 (2007) BindingDB Entry DOI: 10.7270/Q2J38VWN
					More data for this Ligand-Target Pair