Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 382.4 BDBM372594

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372594 (N-[2-(4-Fluoro-3-methoxy-benzyl)-2H-[1,2,3]triazol...) Show SMILES COc1cc(Cn2ncc(NC(=O)Cc3ccc(cc3)C(C)C)n2)ccc1F Show InChI InChI=1S/C21H23FN4O2/c1-14(2)17-7-4-15(5-8-17)11-21(27)24-20-12-23-26(25-20)13-16-6-9-18(22)19(10-16)28-3/h4-10,12,14H,11,13H2,1-3H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair