Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 457.5 BDBM50414463

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50414463 (CHEMBL557098) Show SMILES COc1cc(NC(=O)C(C)(C)c2ccccc2)ccc1N1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C28H31N3O3/c1-28(2,22-12-8-5-9-13-22)27(33)29-23-14-15-24(25(20-23)34-3)30-16-18-31(19-17-30)26(32)21-10-6-4-7-11-21/h4-15,20H,16-19H2,1-3H3,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human neuropeptide Y2 receptor in KAN-TS cells by [35]GTPgammaS assay				Bioorg Med Chem Lett 19: 4022-5 (2009) Article DOI: 10.1016/j.bmcl.2009.06.035 BindingDB Entry DOI: 10.7270/Q2B27VBW
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