Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 522.4 BDBM50235982

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (RAT)	BDBM50235982 (CHEMBL4085281) Show SMILES COc1cc(NC(=O)c2ccc(c(COC(C)=O)c2)-c2ccccc2C(F)(F)F)ccc1S(N)(=O)=O Show InChI InChI=1S/C24H21F3N2O6S/c1-14(30)35-13-16-11-15(7-9-18(16)19-5-3-4-6-20(19)24(25,26)27)23(31)29-17-8-10-22(36(28,32)33)21(12-17)34-2/h3-12H,13H2,1-2H3,(H,29,31)(H2,28,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
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