Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212036
(2-(3-methoxy-4-(pyrrolidin-1-ylmethyl)phenylamino)...)Show SMILES COc1cc(Nc2ncc(C#N)c(n2)-c2ccccc2)ccc1CN1CCCC1 Show InChI InChI=1S/C23H23N5O/c1-29-21-13-20(10-9-18(21)16-28-11-5-6-12-28)26-23-25-15-19(14-24)22(27-23)17-7-3-2-4-8-17/h2-4,7-10,13,15H,5-6,11-12,16H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 activity |
Bioorg Med Chem Lett 17: 3266-70 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.021
BindingDB Entry DOI: 10.7270/Q2GQ6XFG |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50212036
(2-(3-methoxy-4-(pyrrolidin-1-ylmethyl)phenylamino)...)Show SMILES COc1cc(Nc2ncc(C#N)c(n2)-c2ccccc2)ccc1CN1CCCC1 Show InChI InChI=1S/C23H23N5O/c1-29-21-13-20(10-9-18(21)16-28-11-5-6-12-28)26-23-25-15-19(14-24)22(27-23)17-7-3-2-4-8-17/h2-4,7-10,13,15H,5-6,11-12,16H2,1H3,(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Inhibition of CDK1 activity |
Bioorg Med Chem Lett 17: 3266-70 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.021
BindingDB Entry DOI: 10.7270/Q2GQ6XFG |
More data for this
Ligand-Target Pair | |