Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 311.3 BDBM50262446

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50262446 ((E)-1-(5-((dimethylamino)methyl)-2-hydroxy-4-metho...) Show SMILES COc1cc(O)c(cc1CN(C)C)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C19H21NO3/c1-20(2)13-15-11-16(18(22)12-19(15)23-3)17(21)10-9-14-7-5-4-6-8-14/h4-12,22H,13H2,1-3H3/b10-9+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Inhibition of Cdk1/cyclin B				Bioorg Med Chem 16: 7128-33 (2008) Article DOI: 10.1016/j.bmc.2008.06.055 BindingDB Entry DOI: 10.7270/Q2JQ11XQ
					More data for this Ligand-Target Pair