Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50084912
(3-Dibenzofuran-3-yl-2-[1-phosphono-3-(2,4,5-trimet...)Show SMILES COc1cc(OC)c(OC)cc1CCC(N[C@@H](Cc1ccc2c(c1)oc1ccccc21)C(O)=O)P(O)(O)=O Show InChI InChI=1S/C27H30NO9P/c1-34-22-15-25(36-3)24(35-2)14-17(22)9-11-26(38(31,32)33)28-20(27(29)30)12-16-8-10-19-18-6-4-5-7-21(18)37-23(19)13-16/h4-8,10,13-15,20,26,28H,9,11-12H2,1-3H3,(H,29,30)(H2,31,32,33)/t20-,26?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research
Curated by ChEMBL
| Assay Description
In Vitro inhibition of recombinant human endothelin converting enzyme-1 |
J Med Chem 43: 488-504 (2000)
BindingDB Entry DOI: 10.7270/Q21G0MZR |
More data for this
Ligand-Target Pair | |
Neprilysin
(Rattus norvegicus (Rat)) | BDBM50084912
(3-Dibenzofuran-3-yl-2-[1-phosphono-3-(2,4,5-trimet...)Show SMILES COc1cc(OC)c(OC)cc1CCC(N[C@@H](Cc1ccc2c(c1)oc1ccccc21)C(O)=O)P(O)(O)=O Show InChI InChI=1S/C27H30NO9P/c1-34-22-15-25(36-3)24(35-2)14-17(22)9-11-26(38(31,32)33)28-20(27(29)30)12-16-8-10-19-18-6-4-5-7-21(18)37-23(19)13-16/h4-8,10,13-15,20,26,28H,9,11-12H2,1-3H3,(H,29,30)(H2,31,32,33)/t20-,26?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of rat neutral endopeptidase |
J Med Chem 43: 488-504 (2000)
BindingDB Entry DOI: 10.7270/Q21G0MZR |
More data for this
Ligand-Target Pair | |