Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Bifunctional protein GlmU
(Escherichia coli) | BDBM50075358
(CHEMBL3414907)Show SMILES COc1cc(OC)c(cc1NS(C)(=O)=O)S(=O)(=O)N1[C@H](C)CCc2ccccc12 |r| Show InChI InChI=1S/C19H24N2O6S2/c1-13-9-10-14-7-5-6-8-16(14)21(13)29(24,25)19-11-15(20-28(4,22)23)17(26-2)12-18(19)27-3/h5-8,11-13,20H,9-10H2,1-4H3/t13-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
| Assay Description Inhibition of Escherichia coli GlmU acetyltransferase activity assessed as coenzyme A production using acetyl CoA substrate |
Eur J Med Chem 92: 78-90 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.030 BindingDB Entry DOI: 10.7270/Q2RJ4M55 |
More data for this Ligand-Target Pair | |
Bifunctional protein GlmU
(Escherichia coli) | BDBM50075358
(CHEMBL3414907)Show SMILES COc1cc(OC)c(cc1NS(C)(=O)=O)S(=O)(=O)N1[C@H](C)CCc2ccccc12 |r| Show InChI InChI=1S/C19H24N2O6S2/c1-13-9-10-14-7-5-6-8-16(14)21(13)29(24,25)19-11-15(20-28(4,22)23)17(26-2)12-18(19)27-3/h5-8,11-13,20H,9-10H2,1-4H3/t13-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Indian Institute of Integrative Medicine
Curated by ChEMBL
| Assay Description Inhibition of Escherichia coli GlmU acetyltransferase activity assessed as coenzyme A production using acetyl CoA substrate |
Eur J Med Chem 92: 78-90 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.030 BindingDB Entry DOI: 10.7270/Q2RJ4M55 |
More data for this Ligand-Target Pair | |
Bifunctional protein GlmU
(Streptococcus pneumoniae) | BDBM50365072
(CHEMBL1951161)Show SMILES COc1cc(OC)c(cc1NS(C)(=O)=O)S(=O)(=O)N1C(C)CCc2ccccc12 Show InChI InChI=1S/C19H24N2O6S2/c1-13-9-10-14-7-5-6-8-16(14)21(13)29(24,25)19-11-15(20-28(4,22)23)17(26-2)12-18(19)27-3/h5-8,11-13,20H,9-10H2,1-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Boston
Curated by ChEMBL
| Assay Description Inhibition of Streptococcus pneumoniae acetyltransferase activity of GlmU using acetyl-CoA and glucosamine-1-phosphate after 30 mins by Ellman's meth... |
Bioorg Med Chem Lett 22: 1510-9 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.016 BindingDB Entry DOI: 10.7270/Q23J3DF0 |
More data for this Ligand-Target Pair | |