Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 311.4 BDBM50085275

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50085275 (1-[2-(4-Benzyl-3-methoxy-phenoxy)-ethyl]-pyrrolidi...) Show SMILES COc1cc(OCCN2CCCC2)ccc1Cc1ccccc1 Show InChI InChI=1S/C20H25NO2/c1-22-20-16-19(23-14-13-21-11-5-6-12-21)10-9-18(20)15-17-7-3-2-4-8-17/h2-4,7-10,16H,5-6,11-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity was determined against Leukotriene A4 hydrolase				J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ
					More data for this Ligand-Target Pair