Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM167013
(US9073876, 99 | US9732093, Compound 99)Show SMILES COc1cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)nc(N)n1 Show InChI InChI=1S/C19H19FN6O2/c1-27-15-7-16(26-19(22)25-15)28-18-11(10-3-2-4-10)5-6-12(17(18)20)13-8-24-14(21)9-23-13/h5-10H,2-4H2,1H3,(H2,21,24)(H2,22,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9732093 (2017)
BindingDB Entry DOI: 10.7270/Q2NV9MCX |
More data for this
Ligand-Target Pair | |
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM167013
(US9073876, 99 | US9732093, Compound 99)Show SMILES COc1cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)nc(N)n1 Show InChI InChI=1S/C19H19FN6O2/c1-27-15-7-16(26-19(22)25-15)28-18-11(10-3-2-4-10)5-6-12(17(18)20)13-8-24-14(21)9-23-13/h5-10H,2-4H2,1H3,(H2,21,24)(H2,22,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9073876 (2015)
BindingDB Entry DOI: 10.7270/Q28S4NPC |
More data for this
Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM167013
(US9073876, 99 | US9732093, Compound 99)Show SMILES COc1cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)nc(N)n1 Show InChI InChI=1S/C19H19FN6O2/c1-27-15-7-16(26-19(22)25-15)28-18-11(10-3-2-4-10)5-6-12(17(18)20)13-8-24-14(21)9-23-13/h5-10H,2-4H2,1H3,(H2,21,24)(H2,22,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9732093 (2017)
BindingDB Entry DOI: 10.7270/Q2NV9MCX |
More data for this
Ligand-Target Pair | |