Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 378.3 BDBM420209

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM420209 (US10485800, Cmpd ID FL | US10485800, Example 166) Show SMILES COc1cc(cc(OC)c1OC)-c1c[nH]c2ncc(cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C22H19FN2O3/c1-26-19-9-14(10-20(27-2)21(19)28-3)18-12-25-22-17(18)8-15(11-24-22)13-4-6-16(23)7-5-13/h4-12H,1-3H3,(H,24,25)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
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