Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 561.6 BDBM50469802

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469802 (CHEMBL132582) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)(C)C)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H35N3O5S/c1-20-9-7-8-10-28(20)40(37,38)33-30(36)23-12-11-21(27(17-23)39-6)15-24-18-34(5)26-14-13-22(16-25(24)26)29(35)32-19-31(2,3)4/h7-14,16-18H,15,19H2,1-6H3,(H,32,35)(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
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