Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 547.6 BDBM50469807

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469807 (CHEMBL130140) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)C)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C30H33N3O5S/c1-19(2)17-31-29(34)22-12-13-26-25(15-22)24(18-33(26)4)14-21-10-11-23(16-27(21)38-5)30(35)32-39(36,37)28-9-7-6-8-20(28)3/h6-13,15-16,18-19H,14,17H2,1-5H3,(H,31,34)(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity against leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes using [3H]LTD4 as radio ligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair