Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 561.6 BDBM50469791

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469791 (CHEMBL424257) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCCC(C)C)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H35N3O5S/c1-20(2)14-15-32-30(35)23-12-13-27-26(17-23)25(19-34(27)4)16-22-10-11-24(18-28(22)39-5)31(36)33-40(37,38)29-9-7-6-8-21(29)3/h6-13,17-20H,14-16H2,1-5H3,(H,32,35)(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
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