Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 325.3 BDBM420148

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM420148 (US10485800, Cmpd ID 6-(4-amino-3- methoxyphenyl)-1...) Show SMILES COc1cc(ccc1N)-c1cnc2[nH]c(=O)n(C3CCCC3)c2n1 Show InChI InChI=1S/C17H19N5O2/c1-24-14-8-10(6-7-12(14)18)13-9-19-15-16(20-13)22(17(23)21-15)11-4-2-3-5-11/h6-9,11H,2-5,18H2,1H3,(H,19,21,23)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
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