Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM193428
(US9199944, 10)Show SMILES COc1cc(ccc1Nc1nc(Nc2ccc(cc2)N2CCN(CC2)C(C)=O)ncc1Cl)N1CCN(CC1)C(C)=O Show InChI InChI=1S/C29H35ClN8O3/c1-20(39)35-10-14-37(15-11-35)23-6-4-22(5-7-23)32-29-31-19-25(30)28(34-29)33-26-9-8-24(18-27(26)41-3)38-16-12-36(13-17-38)21(2)40/h4-9,18-19H,10-17H2,1-3H3,(H2,31,32,33,34) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
US Patent
| Assay Description
In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ... |
US Patent US9199944 (2015)
BindingDB Entry DOI: 10.7270/Q2J96558 |
More data for this
Ligand-Target Pair | |
ALK tyrosine kinase receptor [L1196M]
(Homo sapiens (Human)) | BDBM193428
(US9199944, 10)Show SMILES COc1cc(ccc1Nc1nc(Nc2ccc(cc2)N2CCN(CC2)C(C)=O)ncc1Cl)N1CCN(CC1)C(C)=O Show InChI InChI=1S/C29H35ClN8O3/c1-20(39)35-10-14-37(15-11-35)23-6-4-22(5-7-23)32-29-31-19-25(30)28(34-29)33-26-9-8-24(18-27(26)41-3)38-16-12-36(13-17-38)21(2)40/h4-9,18-19H,10-17H2,1-3H3,(H2,31,32,33,34) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 207 | n/a | n/a | n/a | n/a | n/a | 25 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
US Patent
| Assay Description
In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ... |
US Patent US9199944 (2015)
BindingDB Entry DOI: 10.7270/Q2J96558 |
More data for this
Ligand-Target Pair | |