Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM245635
(US9428508, 90)Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)-n1cc(C)nc1C Show InChI InChI=1S/C27H32N8O3S/c1-16(2)34-39(36,37)24-9-7-6-8-22(24)30-26-20-12-13-28-25(20)32-27(33-26)31-21-11-10-19(14-23(21)38-5)35-15-17(3)29-18(35)4/h6-11,14-16,34H,12-13H2,1-5H3,(H3,28,30,31,32,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <20 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |
Focal adhesion kinase 1
(Homo sapiens (Human)) | BDBM245635
(US9428508, 90)Show SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)-n1cc(C)nc1C Show InChI InChI=1S/C27H32N8O3S/c1-16(2)34-39(36,37)24-9-7-6-8-22(24)30-26-20-12-13-28-25(20)32-27(33-26)31-21-11-10-19(14-23(21)38-5)35-15-17(3)29-18(35)4/h6-11,14-16,34H,12-13H2,1-5H3,(H3,28,30,31,32,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <20 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |