Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 375.4 BDBM549576

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM549576 (US11306075, Ex. 23) Show SMILES COc1cc(ccn1)-c1ccc2c(c(CCC(C)=O)oc2c1)-c1ccc(C)o1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WS8XFN
					More data for this Ligand-Target Pair