Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 463.4 BDBM50102679

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional protein GlmU (Escherichia coli)	BDBM50102679 (CHEMBL3343035) Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4ccccc4)cc3)nc(nc2cc1O)-c1ccccn1 Show InChI InChI=1S/C27H21N5O3/c1-35-24-15-20-22(16-23(24)33)31-26(21-9-5-6-14-28-21)32-25(20)29-18-10-12-19(13-11-18)30-27(34)17-7-3-2-4-8-17/h2-16,33H,1H3,(H,30,34)(H,29,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Escherichia coli ATCC 27325 GlmU expressed in Escherichia coli HMS174(DE3) incubated for 15 mins prior to MgCl2 addition measured after...				Bioorg Med Chem 22: 6256-69 (2014) Article DOI: 10.1016/j.bmc.2014.08.017 BindingDB Entry DOI: 10.7270/Q2SN0BR9
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