Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 254.2 BDBM192657Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin L (Capra hircus (Goat))	BDBM192657 (N’-(4-methoxyphenylmethylene)benzohydrazide (...) Show SMILES COc1ccc(\C=N\NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C15H14N2O2/c1-19-14-9-7-12(8-10-14)11-16-17-15(18)13-5-3-2-4-6-13/h2-11H,1H3,(H,17,18)/b16-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	19.8	-45.7	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin B (Capra hircus (Goat))	BDBM192657 (N’-(4-methoxyphenylmethylene)benzohydrazide (...) Show SMILES COc1ccc(\C=N\NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C15H14N2O2/c1-19-14-9-7-12(8-10-14)11-16-17-15(18)13-5-3-2-4-6-13/h2-11H,1H3,(H,17,18)/b16-11+	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	440	-37.7	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair
Cathepsin H (Capra hircus (Goat))	BDBM192657 (N’-(4-methoxyphenylmethylene)benzohydrazide (...) Show SMILES COc1ccc(\C=N\NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C15H14N2O2/c1-19-14-9-7-12(8-10-14)11-16-17-15(18)13-5-3-2-4-6-13/h2-11H,1H3,(H,17,18)/b16-11+	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.33E+3	-34.9	n/a	n/a	n/a	n/a	n/a	5.0	37
Kurukshetra University					Assay Description The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...				Bioorg Chem 67: 64-74 (2016) Article DOI: 10.1016/j.bioorg.2016.05.003 BindingDB Entry DOI: 10.7270/Q20G3HZB
					More data for this Ligand-Target Pair