Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 687.8 BDBM50554435

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50554435 (CHEMBL4755394) Show SMILES COc1ccc(CC[C@@H](NC(=O)[C@H](CCCc2ccccc2)NC(=O)CN2CCOCC2)C(=O)N[C@H](Cc2ccc(C)cc2)C(=O)NO)cc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells using 5-FAM/QX...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01285 BindingDB Entry DOI: 10.7270/Q2PK0KTG
					More data for this Ligand-Target Pair