Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Adenosine receptor A2a
(Rattus norvegicus (rat)) | BDBM50221703
(9-(4-methoxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)Show SMILES COc1ccc(CCN2CCCn3c2nc2n(C)c(=O)n(C)c(=O)c32)cc1 Show InChI InChI=1S/C19H23N5O3/c1-21-16-15(17(25)22(2)19(21)26)24-11-4-10-23(18(24)20-16)12-9-13-5-7-14(27-3)8-6-13/h5-8H,4,9-12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College
Curated by ChEMBL
| Assay Description Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatal membrane |
Bioorg Med Chem 15: 6956-74 (2007)
Article DOI: 10.1016/j.bmc.2007.07.051 BindingDB Entry DOI: 10.7270/Q26W99TB |
More data for this Ligand-Target Pair | |
Adenosine receptor A1
(Rattus norvegicus (rat)) | BDBM50221703
(9-(4-methoxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)Show SMILES COc1ccc(CCN2CCCn3c2nc2n(C)c(=O)n(C)c(=O)c32)cc1 Show InChI InChI=1S/C19H23N5O3/c1-21-16-15(17(25)22(2)19(21)26)24-11-4-10-23(18(24)20-16)12-9-13-5-7-14(27-3)8-6-13/h5-8H,4,9-12H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College
Curated by ChEMBL
| Assay Description Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membrane |
Bioorg Med Chem 15: 6956-74 (2007)
Article DOI: 10.1016/j.bmc.2007.07.051 BindingDB Entry DOI: 10.7270/Q26W99TB |
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50221703
(9-(4-methoxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)Show SMILES COc1ccc(CCN2CCCn3c2nc2n(C)c(=O)n(C)c(=O)c32)cc1 Show InChI InChI=1S/C19H23N5O3/c1-21-16-15(17(25)22(2)19(21)26)24-11-4-10-23(18(24)20-16)12-9-13-5-7-14(27-3)8-6-13/h5-8H,4,9-12H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Prolink1-tagged human GPR55 receptor expressed in CHO cells assessed as inhibition of lysophosphatidylinositol-induced beta ar... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00208 BindingDB Entry DOI: 10.7270/Q2PZ5DJH |
More data for this Ligand-Target Pair | |
N-arachidonyl glycine receptor
(Homo sapiens (Human)) | BDBM50221703
(9-(4-methoxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)Show SMILES COc1ccc(CCN2CCCn3c2nc2n(C)c(=O)n(C)c(=O)c32)cc1 Show InChI InChI=1S/C19H23N5O3/c1-21-16-15(17(25)22(2)19(21)26)24-11-4-10-23(18(24)20-16)12-9-13-5-7-14(27-3)8-6-13/h5-8H,4,9-12H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Prolink1-tagged human GPR18 receptor expressed in CHO cells assessed as inhibition of THC-induced beta arrestin recruitment af... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00208 BindingDB Entry DOI: 10.7270/Q2PZ5DJH |
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50221703
(9-(4-methoxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)Show SMILES COc1ccc(CCN2CCCn3c2nc2n(C)c(=O)n(C)c(=O)c32)cc1 Show InChI InChI=1S/C19H23N5O3/c1-21-16-15(17(25)22(2)19(21)26)24-11-4-10-23(18(24)20-16)12-9-13-5-7-14(27-3)8-6-13/h5-8H,4,9-12H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Prolink1-tagged human GPR55 receptor expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by b... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00208 BindingDB Entry DOI: 10.7270/Q2PZ5DJH |
More data for this Ligand-Target Pair | |
N-arachidonyl glycine receptor
(Homo sapiens (Human)) | BDBM50221703
(9-(4-methoxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrah...)Show SMILES COc1ccc(CCN2CCCn3c2nc2n(C)c(=O)n(C)c(=O)c32)cc1 Show InChI InChI=1S/C19H23N5O3/c1-21-16-15(17(25)22(2)19(21)26)24-11-4-10-23(18(24)20-16)12-9-13-5-7-14(27-3)8-6-13/h5-8H,4,9-12H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Prolink1-tagged human GPR18 receptor expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by b... |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.0c00208 BindingDB Entry DOI: 10.7270/Q2PZ5DJH |
More data for this Ligand-Target Pair | |