Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM165035
(US9067917, 70 | US9682971, 70)Show SMILES COc1ccc(Cn2c(CC(C)(C)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)cc1 Show InChI InChI=1S/C30H29N3O4/c1-30(2,29(34)35)17-28-32-26-16-24(37-19-22-11-10-21-6-4-5-7-25(21)31-22)14-15-27(26)33(28)18-20-8-12-23(36-3)13-9-20/h4-16H,17-19H2,1-3H3,(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| 650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9682971 (2017)
BindingDB Entry DOI: 10.7270/Q2P26W84 |
More data for this
Ligand-Target Pair | |
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM165035
(US9067917, 70 | US9682971, 70)Show SMILES COc1ccc(Cn2c(CC(C)(C)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)cc1 Show InChI InChI=1S/C30H29N3O4/c1-30(2,29(34)35)17-28-32-26-16-24(37-19-22-11-10-21-6-4-5-7-25(21)31-22)14-15-27(26)33(28)18-20-8-12-23(36-3)13-9-20/h4-16H,17-19H2,1-3H3,(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9067917 (2015)
BindingDB Entry DOI: 10.7270/Q24748M5 |
More data for this
Ligand-Target Pair | |