Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 364.4 BDBM372471

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372471 (2-(4-Isopropyl-phenyl)-N-[2-(4-methoxy-benzyl)-2H-...) Show SMILES COc1ccc(Cn2ncc(NC(=O)Cc3ccc(cc3)C(C)C)n2)cc1 Show InChI InChI=1S/C21H24N4O2/c1-15(2)18-8-4-16(5-9-18)12-21(26)23-20-13-22-25(24-20)14-17-6-10-19(27-3)11-7-17/h4-11,13,15H,12,14H2,1-3H3,(H,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair