Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 392.4 BDBM372506

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372506 (N-[2-(4-Methoxy-benzyl)-2H-[1,2,3]triazol-4-yl]-2-...) Show SMILES COc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCCC3)n2)cc1 Show InChI InChI=1S/C21H24N6O2/c1-29-18-7-4-16(5-8-18)15-27-23-14-19(25-27)24-21(28)12-17-6-9-20(22-13-17)26-10-2-3-11-26/h4-9,13-14H,2-3,10-12,15H2,1H3,(H,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair