Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 520.9 BDBM532171

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM532171 (US11208422, Example 19) Show SMILES COc1ccc(F)c(n1)C(=O)N1CCC2CCC1CN2Cc1c(nc2ccccn12)-c1ccc(Cl)cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM532171 (US11208422, Example 19) Show SMILES COc1ccc(F)c(n1)C(=O)N1CCC2CCC1CN2Cc1c(nc2ccccn12)-c1ccc(Cl)cn1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were conducted using stably transfected CHO cells. The compounds o...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XHD
					More data for this Ligand-Target Pair