Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM167771
(US9073922, 261 | US9796708, Example 261)Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1=C[C@@H](CO)N(CC(=O)N(C)C)CC1 |t:21| Show InChI InChI=1S/C24H27FN4O3/c1-28(2)23(31)13-29-9-7-15(10-17(29)14-30)21-12-20-18(6-8-26-24(20)27-21)19-11-16(25)4-5-22(19)32-3/h4-6,8,10-12,17,30H,7,9,13-14H2,1-3H3,(H,26,27)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.
US Patent
| Assay Description
CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in... |
US Patent US9796708 (2017)
BindingDB Entry DOI: 10.7270/Q2WD42P4 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM167771
(US9073922, 261 | US9796708, Example 261)Show SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1=C[C@@H](CO)N(CC(=O)N(C)C)CC1 |t:21| Show InChI InChI=1S/C24H27FN4O3/c1-28(2)23(31)13-29-9-7-15(10-17(29)14-30)21-12-20-18(6-8-26-24(20)27-21)19-11-16(25)4-5-22(19)32-3/h4-6,8,10-12,17,30H,7,9,13-14H2,1-3H3,(H,26,27)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie, Inc.
US Patent
| Assay Description
CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in... |
US Patent US9073922 (2015)
BindingDB Entry DOI: 10.7270/Q2CJ8C78 |
More data for this
Ligand-Target Pair | |