Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mineralocorticoid receptor
(Homo sapiens (Human)) | BDBM50219464
(6-(5-fluoro-2-methoxyphenyl)-6-methyl-1-phenyl-4-(...)Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CCCc1ccccc1)C(F)(F)F |w:13.14| Show InChI InChI=1S/C22H26F4O2/c1-20(2,18-14-17(23)11-12-19(18)28-3)15-21(27,22(24,25)26)13-7-10-16-8-5-4-6-9-16/h4-6,8-9,11-12,14,27H,7,10,13,15H2,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >740 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Displacement of TAMRA labeled mifepristone at human mineralocorticoid receptor in insect cell |
Bioorg Med Chem Lett 17: 5025-31 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.031 BindingDB Entry DOI: 10.7270/Q2G73FJ2 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50219464
(6-(5-fluoro-2-methoxyphenyl)-6-methyl-1-phenyl-4-(...)Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CCCc1ccccc1)C(F)(F)F |w:13.14| Show InChI InChI=1S/C22H26F4O2/c1-20(2,18-14-17(23)11-12-19(18)28-3)15-21(27,22(24,25)26)13-7-10-16-8-5-4-6-9-16/h4-6,8-9,11-12,14,27H,7,10,13,15H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >740 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Displacement of TAMRA labeled Dexamethasone at human progesterone receptor in insect cell |
Bioorg Med Chem Lett 17: 5025-31 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.031 BindingDB Entry DOI: 10.7270/Q2G73FJ2 |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50219464
(6-(5-fluoro-2-methoxyphenyl)-6-methyl-1-phenyl-4-(...)Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(CCCc1ccccc1)C(F)(F)F |w:13.14| Show InChI InChI=1S/C22H26F4O2/c1-20(2,18-14-17(23)11-12-19(18)28-3)15-21(27,22(24,25)26)13-7-10-16-8-5-4-6-9-16/h4-6,8-9,11-12,14,27H,7,10,13,15H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cell |
Bioorg Med Chem Lett 17: 5025-31 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.031 BindingDB Entry DOI: 10.7270/Q2G73FJ2 |
More data for this Ligand-Target Pair | |