Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 658.6 BDBM50323881

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50323881 (CHEMBL1214477 | N-(3-(((3S,4R)-6-((5,6-difluoroben...) Show SMILES COc1ccc(NS(=O)(=O)C(F)(F)F)cc1C[C@H]1[C@@H](CO)c2cc(OCc3nc4cc(F)c(F)cc4s3)ccc2OC1(C)C |r| Show InChI InChI=1S/C29H27F5N2O6S2/c1-28(2)20(9-15-8-16(4-6-24(15)40-3)36-44(38,39)29(32,33)34)19(13-37)18-10-17(5-7-25(18)42-28)41-14-27-35-23-11-21(30)22(31)12-26(23)43-27/h4-8,10-12,19-20,36-37H,9,13-14H2,1-3H3/t19-,20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...				Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0
					More data for this Ligand-Target Pair