Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50392631
(CHEMBL2153524)Show InChI InChI=1S/C17H14N4O2S/c1-22-12-6-5-10(8-13(12)23-2)21-16-15-14(19-9-20-16)11-4-3-7-18-17(11)24-15/h3-9H,1-2H3,(H,19,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma32P]ATP after 30 mins by sc... |
Eur J Med Chem 58: 171-83 (2012)
Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50392631
(CHEMBL2153524)Show InChI InChI=1S/C17H14N4O2S/c1-22-12-6-5-10(8-13(12)23-2)21-16-15-14(19-9-20-16)11-4-3-7-18-17(11)24-15/h3-9H,1-2H3,(H,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma32P]ATP after 30 mins by scin... |
Eur J Med Chem 58: 171-83 (2012)
Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50392631
(CHEMBL2153524)Show InChI InChI=1S/C17H14N4O2S/c1-22-12-6-5-10(8-13(12)23-2)21-16-15-14(19-9-20-16)11-4-3-7-18-17(11)24-15/h3-9H,1-2H3,(H,19,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CDK5/p25 expressed in Escherichia coli using histone H1 as substrate and [gamma32P]ATP after 30 mins by sc... |
Eur J Med Chem 58: 171-83 (2012)
Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ |
More data for this Ligand-Target Pair | |