Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50443929
(CHEMBL3091802)Show SMILES COc1ccc(Nc2ncnc3c4ncc(cc4oc23)-c2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C24H18N4O5/c1-29-16-6-4-15(9-18(16)30-2)28-24-23-22(26-11-27-24)21-20(33-23)8-14(10-25-21)13-3-5-17-19(7-13)32-12-31-17/h3-11H,12H2,1-2H3,(H,26,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK5/p25 using [gamma-33P]ATP as substrate after 30 mins by scintillation counting analysis |
Bioorg Med Chem Lett 23: 6784-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.019
BindingDB Entry DOI: 10.7270/Q2MC91HJ |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50443929
(CHEMBL3091802)Show SMILES COc1ccc(Nc2ncnc3c4ncc(cc4oc23)-c2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C24H18N4O5/c1-29-16-6-4-15(9-18(16)30-2)28-24-23-22(26-11-27-24)21-20(33-23)8-14(10-25-21)13-3-5-17-19(7-13)32-12-31-17/h3-11H,12H2,1-2H3,(H,26,27,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Bioorg Med Chem Lett 23: 6784-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.019
BindingDB Entry DOI: 10.7270/Q2MC91HJ |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50443929
(CHEMBL3091802)Show SMILES COc1ccc(Nc2ncnc3c4ncc(cc4oc23)-c2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C24H18N4O5/c1-29-16-6-4-15(9-18(16)30-2)28-24-23-22(26-11-27-24)21-20(33-23)8-14(10-25-21)13-3-5-17-19(7-13)32-12-31-17/h3-11H,12H2,1-2H3,(H,26,27,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description
Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti... |
Bioorg Med Chem Lett 23: 6784-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.10.019
BindingDB Entry DOI: 10.7270/Q2MC91HJ |
More data for this
Ligand-Target Pair | |