Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50450220
(CHEMBL4159072)Show SMILES COc1ccc(Oc2ccc3nc(COc4cccc(c4)C(O)=O)n(C)c3c2)cc1 Show InChI InChI=1S/C23H20N2O5/c1-25-21-13-19(30-17-8-6-16(28-2)7-9-17)10-11-20(21)24-22(25)14-29-18-5-3-4-15(12-18)23(26)27/h3-13H,14H2,1-2H3,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 307 | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 5079-5098 (2018)
Article DOI: 10.1016/j.bmc.2018.09.006
BindingDB Entry DOI: 10.7270/Q2J968XC |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50450220
(CHEMBL4159072)Show SMILES COc1ccc(Oc2ccc3nc(COc4cccc(c4)C(O)=O)n(C)c3c2)cc1 Show InChI InChI=1S/C23H20N2O5/c1-25-21-13-19(30-17-8-6-16(28-2)7-9-17)10-11-20(21)24-22(25)14-29-18-5-3-4-15(12-18)23(26)27/h3-13H,14H2,1-2H3,(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Agonist activity at recombinant human GAL4-DBD fused PPARalpha LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assay |
Bioorg Med Chem 26: 5079-5098 (2018)
Article DOI: 10.1016/j.bmc.2018.09.006
BindingDB Entry DOI: 10.7270/Q2J968XC |
More data for this
Ligand-Target Pair | |