Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 378.7 BDBM50550745

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA (cytosine-5)-methyltransferase 3B (Homo sapiens (Human))	BDBM50550745 (CHEMBL4745197) Show SMILES COc1ccc(c(c1)C1Oc2ccccc2C(=O)C1(Cl)[N+]([O-])=O)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DNMT3B expressed in Escherichia coli Rosetta-gamiTM 2(DE3) pLysS competent cells using biotinylated 6-FAM double strand DNA compr...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111829 BindingDB Entry DOI: 10.7270/Q2NS0ZHR
					More data for this Ligand-Target Pair