Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50070578
(CHEMBL3408795)Show InChI InChI=1S/C16H12N4OS/c1-21-11-4-2-9(3-5-11)10-6-12-13-14(15(17)20-8-19-13)22-16(12)18-7-10/h2-8H,1H3,(H2,17,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50070578
(CHEMBL3408795)Show InChI InChI=1S/C16H12N4OS/c1-21-11-4-2-9(3-5-11)10-6-12-13-14(15(17)20-8-19-13)22-16(12)18-7-10/h2-8H,1H3,(H2,17,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti... |
Eur J Med Chem 92: 124-34 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.038 BindingDB Entry DOI: 10.7270/Q2BR8TVG |
More data for this Ligand-Target Pair | |