Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50312403
(2-(4-((5-(Benzofuran-2-yl)-4-(4-methoxyphenyl)thia...)Show SMILES COc1ccc(cc1)-c1nc(COc2ccc(OCC(O)=O)c(C)c2)sc1-c1cc2ccccc2o1 Show InChI InChI=1S/C28H23NO6S/c1-17-13-21(11-12-22(17)34-16-26(30)31)33-15-25-29-27(18-7-9-20(32-2)10-8-18)28(36-25)24-14-19-5-3-4-6-23(19)35-24/h3-14H,15-16H2,1-2H3,(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... |
J Med Chem 53: 77-105 (2010)
Article DOI: 10.1021/jm9007399
BindingDB Entry DOI: 10.7270/Q28052RP |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50312403
(2-(4-((5-(Benzofuran-2-yl)-4-(4-methoxyphenyl)thia...)Show SMILES COc1ccc(cc1)-c1nc(COc2ccc(OCC(O)=O)c(C)c2)sc1-c1cc2ccccc2o1 Show InChI InChI=1S/C28H23NO6S/c1-17-13-21(11-12-22(17)34-16-26(30)31)33-15-25-29-27(18-7-9-20(32-2)10-8-18)28(36-25)24-14-19-5-3-4-6-23(19)35-24/h3-14H,15-16H2,1-2H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... |
J Med Chem 53: 77-105 (2010)
Article DOI: 10.1021/jm9007399
BindingDB Entry DOI: 10.7270/Q28052RP |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50312403
(2-(4-((5-(Benzofuran-2-yl)-4-(4-methoxyphenyl)thia...)Show SMILES COc1ccc(cc1)-c1nc(COc2ccc(OCC(O)=O)c(C)c2)sc1-c1cc2ccccc2o1 Show InChI InChI=1S/C28H23NO6S/c1-17-13-21(11-12-22(17)34-16-26(30)31)33-15-25-29-27(18-7-9-20(32-2)10-8-18)28(36-25)24-14-19-5-3-4-6-23(19)35-24/h3-14H,15-16H2,1-2H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description
Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... |
J Med Chem 53: 77-105 (2010)
Article DOI: 10.1021/jm9007399
BindingDB Entry DOI: 10.7270/Q28052RP |
More data for this
Ligand-Target Pair | |