Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50312490
(2-(4-((5-(4-(Trifluoromethyl)phenyl)-4-(4-methoxyp...)Show SMILES COc1ccc(cc1)-c1nc(COc2ccc(OCC(O)=O)cc2)sc1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H20F3NO5S/c1-33-19-8-4-16(5-9-19)24-25(17-2-6-18(7-3-17)26(27,28)29)36-22(30-24)14-34-20-10-12-21(13-11-20)35-15-23(31)32/h2-13H,14-15H2,1H3,(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... |
J Med Chem 53: 77-105 (2010)
Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50312490
(2-(4-((5-(4-(Trifluoromethyl)phenyl)-4-(4-methoxyp...)Show SMILES COc1ccc(cc1)-c1nc(COc2ccc(OCC(O)=O)cc2)sc1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H20F3NO5S/c1-33-19-8-4-16(5-9-19)24-25(17-2-6-18(7-3-17)26(27,28)29)36-22(30-24)14-34-20-10-12-21(13-11-20)35-15-23(31)32/h2-13H,14-15H2,1H3,(H,31,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... |
J Med Chem 53: 77-105 (2010)
Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50312490
(2-(4-((5-(4-(Trifluoromethyl)phenyl)-4-(4-methoxyp...)Show SMILES COc1ccc(cc1)-c1nc(COc2ccc(OCC(O)=O)cc2)sc1-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H20F3NO5S/c1-33-19-8-4-16(5-9-19)24-25(17-2-6-18(7-3-17)26(27,28)29)36-22(30-24)14-34-20-10-12-21(13-11-20)35-15-23(31)32/h2-13H,14-15H2,1H3,(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 930 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... |
J Med Chem 53: 77-105 (2010)
Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP |
More data for this Ligand-Target Pair | |