Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 391.5 BDBM50327307

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Homo sapiens (Human))	BDBM50327307 (4-((dimethylamino)methyl)-N-((1-(4-methoxyphenyl)-...) Show SMILES COc1ccc(cc1)-n1c(C)cc(CNC(=O)c2ccc(CN(C)C)cc2)c1C Show InChI InChI=1S/C24H29N3O2/c1-17-14-21(18(2)27(17)22-10-12-23(29-5)13-11-22)15-25-24(28)20-8-6-19(7-9-20)16-26(3)4/h6-14H,15-16H2,1-5H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Microbial Chemistry Curated by ChEMBL					Assay Description Inhibition of OSC				Bioorg Med Chem Lett 20: 5807-10 (2010) Article DOI: 10.1016/j.bmcl.2010.07.131 BindingDB Entry DOI: 10.7270/Q2Q52PV3
					More data for this Ligand-Target Pair