Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 379.4 BDBM50401702

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50401702 (CHEMBL2205918) Show SMILES COc1ccc(cc1)-n1cnc2c(sc3ncnc(NC4CCC4)c23)c1=O Show InChI InChI=1S/C19H17N5O2S/c1-26-13-7-5-12(6-8-13)24-10-22-15-14-17(23-11-3-2-4-11)20-9-21-18(14)27-16(15)19(24)25/h5-11H,2-4H2,1H3,(H,20,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1				Bioorg Med Chem Lett 22: 7223-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.048 BindingDB Entry DOI: 10.7270/Q24B32GJ
					More data for this Ligand-Target Pair