Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM50019882
(CHEMBL3287175 | US9745282, 25)Show InChI InChI=1S/C21H18N2O2/c1-25-19-7-4-15(5-8-19)21(24)23-12-10-17-13-16(6-9-20(17)23)18-3-2-11-22-14-18/h2-9,11,13-14H,10,12H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University
Curated by ChEMBL
| Assay Description Inhibition of human CYP11B2 expressed in hamster V79MZh cells using deoxycorticosterone as substrate |
J Med Chem 57: 5179-89 (2014)
Article DOI: 10.1021/jm500140c BindingDB Entry DOI: 10.7270/Q20Z74VS |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM50019882
(CHEMBL3287175 | US9745282, 25)Show InChI InChI=1S/C21H18N2O2/c1-25-19-7-4-15(5-8-19)21(24)23-12-10-17-13-16(6-9-20(17)23)18-3-2-11-22-14-18/h2-9,11,13-14H,10,12H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp; ElexoPharm GmbH
US Patent
| Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ... |
US Patent US9745282 (2017)
BindingDB Entry DOI: 10.7270/Q25Q4Z66 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM50019882
(CHEMBL3287175 | US9745282, 25)Show InChI InChI=1S/C21H18N2O2/c1-25-19-7-4-15(5-8-19)21(24)23-12-10-17-13-16(6-9-20(17)23)18-3-2-11-22-14-18/h2-9,11,13-14H,10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp; ElexoPharm GmbH
US Patent
| |
US Patent US9745282 (2017)
BindingDB Entry DOI: 10.7270/Q25Q4Z66 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM50019882
(CHEMBL3287175 | US9745282, 25)Show InChI InChI=1S/C21H18N2O2/c1-25-19-7-4-15(5-8-19)21(24)23-12-10-17-13-16(6-9-20(17)23)18-3-2-11-22-14-18/h2-9,11,13-14H,10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University
Curated by ChEMBL
| Assay Description Inhibition of human CYP11B1 expressed in hamster V79MZh cells using deoxycorticosterone as substrate |
J Med Chem 57: 5179-89 (2014)
Article DOI: 10.1021/jm500140c BindingDB Entry DOI: 10.7270/Q20Z74VS |
More data for this Ligand-Target Pair | |