Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Plasmepsin II
(Plasmodium falciparum) | BDBM234511
(US9353089, 158)Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CC2)C1=O)c1ccc(OC)cc1 Show InChI InChI=1S/C20H21N3O3/c1-25-16-9-3-13(4-10-16)20(14-5-11-17(26-2)12-6-14)18(24)23(15-7-8-15)19(21)22-20/h3-6,9-12,15H,7-8H2,1-2H3,(H2,21,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 392 | n/a | n/a | n/a | n/a | 4.5 | 25 |
Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
US Patent
| Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and... |
US Patent US9353089 (2016)
BindingDB Entry DOI: 10.7270/Q2GQ6WP6 |
More data for this
Ligand-Target Pair | |
Beta-secretase 1
(Homo sapiens (Human)) | BDBM234511
(US9353089, 158)Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CC2)C1=O)c1ccc(OC)cc1 Show InChI InChI=1S/C20H21N3O3/c1-25-16-9-3-13(4-10-16)20(14-5-11-17(26-2)12-6-14)18(24)23(15-7-8-15)19(21)22-20/h3-6,9-12,15H,7-8H2,1-2H3,(H2,21,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 4.0 | 25 |
Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
US Patent
| Assay Description
The recombinant human BACE1, Cathepsin D, and Cathepsin E enzymes were purchased from R&D Systems (catalog numbers are 931-AS, 1014AS and 1294AS, res... |
US Patent US9353089 (2016)
BindingDB Entry DOI: 10.7270/Q2GQ6WP6 |
More data for this
Ligand-Target Pair | |