Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Plasmepsin IV [1-448]
(Plasmodium falciparum) | BDBM234528
(US9353089, 207)Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCNCC2)C1=O)c1ccc(OC)cc1 Show InChI InChI=1S/C22H26N4O3/c1-28-18-7-3-15(4-8-18)22(16-5-9-19(29-2)10-6-16)20(27)26(21(23)25-22)17-11-13-24-14-12-17/h3-10,17,24H,11-14H2,1-2H3,(H2,23,25) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 192 | n/a | n/a | n/a | n/a | 4.5 | 25 |
Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
US Patent
| Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and... |
US Patent US9353089 (2016)
BindingDB Entry DOI: 10.7270/Q2GQ6WP6 |
More data for this
Ligand-Target Pair | |
Plasmepsin II
(Plasmodium falciparum) | BDBM234528
(US9353089, 207)Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCNCC2)C1=O)c1ccc(OC)cc1 Show InChI InChI=1S/C22H26N4O3/c1-28-18-7-3-15(4-8-18)22(16-5-9-19(29-2)10-6-16)20(27)26(21(23)25-22)17-11-13-24-14-12-17/h3-10,17,24H,11-14H2,1-2H3,(H2,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 505 | n/a | n/a | n/a | n/a | 4.5 | 25 |
Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
US Patent
| Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and... |
US Patent US9353089 (2016)
BindingDB Entry DOI: 10.7270/Q2GQ6WP6 |
More data for this
Ligand-Target Pair | |
Plasmepsin II
(Plasmodium falciparum) | BDBM234528
(US9353089, 207)Show SMILES COc1ccc(cc1)C1(NC(=N)N(C2CCNCC2)C1=O)c1ccc(OC)cc1 Show InChI InChI=1S/C22H26N4O3/c1-28-18-7-3-15(4-8-18)22(16-5-9-19(29-2)10-6-16)20(27)26(21(23)25-22)17-11-13-24-14-12-17/h3-10,17,24H,11-14H2,1-2H3,(H2,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 505 | n/a | n/a | n/a | n/a | 4.5 | 25 |
Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
US Patent
| Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and... |
US Patent US9353089 (2016)
BindingDB Entry DOI: 10.7270/Q2GQ6WP6 |
More data for this
Ligand-Target Pair | |