Found 8 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ras-related protein Rab-2A
(Canis lupus familiaris) | BDBM54610
(2,3-dimethoxy-6-[5-(4-methoxyphenyl)-2-phenyl-2-py...)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(OC)c(OC)c1C(O)=O)c1ccccc1 |t:9| Show InChI InChI=1S/C25H24N2O5/c1-30-18-11-9-16(10-12-18)20-15-21(27(26-20)17-7-5-4-6-8-17)19-13-14-22(31-2)24(32-3)23(19)25(28)29/h4-14,21H,15H2,1-3H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| Purchase
PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2016)
BindingDB Entry DOI: 10.7270/Q2ZW1JC6 |
More data for this
Ligand-Target Pair | |
GTPase KRas [1-37]
(Homo sapiens (Human)) | BDBM54610
(2,3-dimethoxy-6-[5-(4-methoxyphenyl)-2-phenyl-2-py...)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(OC)c(OC)c1C(O)=O)c1ccccc1 |t:9| Show InChI InChI=1S/C25H24N2O5/c1-30-18-11-9-16(10-12-18)20-15-21(27(26-20)17-7-5-4-6-8-17)19-13-14-22(31-2)24(32-3)23(19)25(28)29/h4-14,21H,15H2,1-3H3,(H,28,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2KK9971 |
More data for this
Ligand-Target Pair | |
Ras-related C3 botulinum toxin substrate 1
(Mus musculus) | BDBM54610
(2,3-dimethoxy-6-[5-(4-methoxyphenyl)-2-phenyl-2-py...)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(OC)c(OC)c1C(O)=O)c1ccccc1 |t:9| Show InChI InChI=1S/C25H24N2O5/c1-30-18-11-9-16(10-12-18)20-15-21(27(26-20)17-7-5-4-6-8-17)19-13-14-22(31-2)24(32-3)23(19)25(28)29/h4-14,21H,15H2,1-3H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2B56H55 |
More data for this
Ligand-Target Pair | |
Ras-related protein Rab-7a
(Canis lupus familiaris) | BDBM54610
(2,3-dimethoxy-6-[5-(4-methoxyphenyl)-2-phenyl-2-py...)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(OC)c(OC)c1C(O)=O)c1ccccc1 |t:9| Show InChI InChI=1S/C25H24N2O5/c1-30-18-11-9-16(10-12-18)20-15-21(27(26-20)17-7-5-4-6-8-17)19-13-14-22(31-2)24(32-3)23(19)25(28)29/h4-14,21H,15H2,1-3H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2MK6B9H |
More data for this
Ligand-Target Pair | |
Ras-related C3 botulinum toxin substrate 1
(Mus musculus) | BDBM54610
(2,3-dimethoxy-6-[5-(4-methoxyphenyl)-2-phenyl-2-py...)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(OC)c(OC)c1C(O)=O)c1ccccc1 |t:9| Show InChI InChI=1S/C25H24N2O5/c1-30-18-11-9-16(10-12-18)20-15-21(27(26-20)17-7-5-4-6-8-17)19-13-14-22(31-2)24(32-3)23(19)25(28)29/h4-14,21H,15H2,1-3H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2959G0B |
More data for this
Ligand-Target Pair | |
Cell division control protein 42 homolog
(Homo sapiens (Human)) | BDBM54610
(2,3-dimethoxy-6-[5-(4-methoxyphenyl)-2-phenyl-2-py...)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(OC)c(OC)c1C(O)=O)c1ccccc1 |t:9| Show InChI InChI=1S/C25H24N2O5/c1-30-18-11-9-16(10-12-18)20-15-21(27(26-20)17-7-5-4-6-8-17)19-13-14-22(31-2)24(32-3)23(19)25(28)29/h4-14,21H,15H2,1-3H3,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2QJ7FRJ |
More data for this
Ligand-Target Pair | |
Cell division control protein 42 homolog
(Homo sapiens (Human)) | BDBM54610
(2,3-dimethoxy-6-[5-(4-methoxyphenyl)-2-phenyl-2-py...)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(OC)c(OC)c1C(O)=O)c1ccccc1 |t:9| Show InChI InChI=1S/C25H24N2O5/c1-30-18-11-9-16(10-12-18)20-15-21(27(26-20)17-7-5-4-6-8-17)19-13-14-22(31-2)24(32-3)23(19)25(28)29/h4-14,21H,15H2,1-3H3,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2G15Z8C |
More data for this
Ligand-Target Pair | |
GTPase KRas [1-37]
(Homo sapiens (Human)) | BDBM54610
(2,3-dimethoxy-6-[5-(4-methoxyphenyl)-2-phenyl-2-py...)Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(OC)c(OC)c1C(O)=O)c1ccccc1 |t:9| Show InChI InChI=1S/C25H24N2O5/c1-30-18-11-9-16(10-12-18)20-15-21(27(26-20)17-7-5-4-6-8-17)19-13-14-22(31-2)24(32-3)23(19)25(28)29/h4-14,21H,15H2,1-3H3,(H,28,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q22N50Q3 |
More data for this
Ligand-Target Pair | |